Biopsy, a cancer journal entry by robert vaughn young. Nicholas bullock, jonathan potts, andrew j simpkin, anthony koupparis. Cancer research is basic research into cancer in order to identify causes and develop strategies for prevention, diagnosis, treatments and cure. Epidemiology of prostate cancer and benign prostatic hyperplasia. Epidemiology of prostate cancer and benign prostatic hyperplasia jmaj 526. The discovery of smallmolecule anticancer drugs, which target specific oncogenic driver mutations, dramatically changed the clinical therapeutic modality pdf. The set of journals have been ranked according to their sjr and divided into four equal groups, four quartiles. The prostate is the gland below a mans bladder that produces fluid for semen. Srpk1, a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion. May 16, 2017 in this special theme issue of the world journal of urology, we explore several aspects of prostate cancer global epidemiology in detail.
Find another journal best suited to publish your research. Pdf epidemiology, etiology, diagnosis and treatment of. The prostate is about the size of a walnut and lies just behind the urinary bladder. Journal of cancer research and clinical oncology springer medizin. Prostate cancer diagnosis memorial sloan kettering. In a study in the journal cancer, researchers at duke university medical center and elsewhere analyzed the records of 1,319 men who had their prostates removed between 1988 and 2008 and found that 304 of them had a rising psa level after surgery, which generally indicates that the cancer has reoccurred and spread.
The advances that have been made in detecting prostate cancer have led to. In 1997 more than 209 900 american men were diagnosed with prostate cancer and more than 41 800 died from the. Prostate cancer journal articles worldwide trends in penile implantation surgery a new study examines the global trends in penile prosthesis implantation in recent years. More advanced clinically then current us patients only 5% of men had screen detected pc advantage largely in men in the prostate, an exocrine gland in the male reproductive system. Oct 07, 2009 agespecific prostate cancer incidence and treatment data from the national cancer institutes surveillance, epidemiology, and end results program and agespecific population estimates from the us census were used to estimate the excess number of men diagnosed and treated each year after the introduction of prostate specific antigen screening. An international journal in cancer research and oncology. Journal of clinical pathology may 2017, 70 5 383389. In some men, it will be advanced when it is first diagnosed. Raceethnicity prostate cancer develops more often in africanamerican men and in caribbean men of african ancestry than in men of other races. This readership is 10 times more when compared to other subscription journals source. Prostate cancer journal articles worldwide trends in penile implantation surgery a new study examines the global trends in penile prosthesis implantation in. Q1 green comprises the quarter of the journals with the highest values, q2 yellow the second highest values, q3 orange the third highest values and q4 red the lowest values. Causes and risk factors we dont know the cause of prostate cancer in. Along with the testicles and the seminal vesicles, the prostate secretes the fluid that makes up semen.
Eighty per cent of men did not know the function of the prostate, and 48% failed to identify prostate cancer as the most common internal cancer in men. University of texas health science center at san antonio. A prostatespecific antigen, distinct from acid phosphatase, was identified by immunologic procedures in prostate tissues normal, benign hypertrophic, and cancerous and seminal plasma, as well as in sera of patients with prostatic cancer and of nude mice bearing human prostatic tumor. Symptoms may include frequent need to urinate, incontinence, pain, blood in the urine, fatigue, and more. Knowledge and attitudes of men about prostate cancer, and predictors of knowledge. Prostate cancer provides a multidisciplinary platform for scientists, surgeons, oncologists and clinicians working on prostate cancer.
Biopsy, a prostate cancer journal entry by robert vaughn young. Prostate cancer in primary care pubmed central pmc. Department of plant pathology, bangladesh agricultural university, mymensingh, bangladesh close. New england journal of medicine letter calls prostate.
Early stage prostate cancer n695 deaths at median 8. To ascertain the current level of understanding among older men about prostate cancer, including treatment options and their potential side effects. Age and family his tory are the main risk factors find, read and cite all the research. Journal of experimental and clinical cancer research is ranked in the first quartile of oncology journals in journal citation reports and is the official.
Racial variation is also pronounced, with black men of african ancestry in the usa having 58% greater incidence and 144%. About 6 in 10 cases of prostate cancer are found in men older than 65. Knowledge and attitudes of men about prostate cancer the. Pdf prostate cancer is the most frequent tumor found in men worldwide and in mexico in particular. In this new study published in the october 2018 issue of european urology, men who engaged most frequently in vigorous activities had a 30% lower risk of advanced prostate cancer, a 25% lower risk of developing advanced prostate cancer, and a 25% lower.
In the past few years, regular prostate cancer screening specifically the psa blood test has gone from being the standard to being scorned. Good nutrition may reduce the incidence of prostate cancer and help reduce the risk of prostate cancer progression. New england journal of medicine letter calls prostate cancer screening guidelines into question newyorkpresbyterian and weill cornell medicine urologists urge reconsideration of prostate cancer. Prostate cancer develops from the gland cells, medically it is also called as adenocarcinoma. Prostate cancer is usually diagnosed in the early stages. It is not intended as anything than a record of my states of mind as i struggled with the disease and the effects of the treatment. List of books and articles about prostate cancer online.
Risk factors for developing prostate cancer include being over 65 years of age, family history, and being africanamerican. Research includes diagnosis, surgery, radiotherapy, drug discovery and medical management of the disease. An estimated 174,650 new cases of prostate cancer will be diagnosed in 2019, accounting for 20% of new cancer cases in men. Prostate cancer treatment study changing the way doctors practice. The incidence has risen in recent decades, mainly fuelled by more widespread use of prostatespecific antigen psa testing, although prostate cancer mortality rates have remained relatively static over that time period. Prostate cancer is characterized by uncontrolled growth of cells in the prostate gland. The prostate health index phi is a new combination of three blood tests that. Prostate cancer is the most common cancer in men after skin cancer. This is one of several essays from my private cancer journal.
This test can help reduce the number of unnecessary biopsies by providing information to improve decisionmaking before ordering a prostate biopsy. It serves as an international medium for these studies, presenting comprehensive coverage of clinical, anatomic, embryologic, physiologic, endocrinologic, and biochemical studies. Prostate cancer is the second most common cause of cancer deaths in men in most developed countries, and the incidence has increased significantly over recent years. Prostate cancer is a common malignancy seen worldwide. The 4kscore test is a blood test that delivers a patientspecific risk score for having aggressive prostate cancer.
Advances in radiotherapy for prostate cancer treatment. Prostate cancer centre a community based outreach clinic, the prostate cancer centre is a partnership between the london hospitals, and hosts cancer prevention trials, patient education sessions and well followup clinics. Prostate cancer prostate cancer symptoms medlineplus. In unscreened populations prostate cancer has the steepest ageincidence curve of all cancers and increases at approximately the 6 th power of age. Agespecific prostate cancer incidence and treatment data from the national cancer institutes surveillance, epidemiology, and end results program and agespecific population estimates from the us census were used to estimate the excess number of men diagnosed and treated each year after the introduction of prostatespecific antigen screening. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatment. A new paper from researchers at harvard university confirms earlier evidence that exercise is protective against prostate cancer mortality. Prostate cancer is a malignancy of one of the major male sex glands. A prostate specific antigen, distinct from acid phosphatase, was identified by immunologic procedures in prostate tissues normal, benign hypertrophic, and cancerous and seminal plasma, as well as in sera of patients with prostatic cancer and of nude mice bearing human prostatic tumor. It is published four times per year, march 30, june 30, september 30. Full text in epub is free except for the current issue. Prostate cancer causes, risk factors, and prevention. More advanced clinically then current us patients only 5% of men had screen detected pc advantage largely in men journal of medicine found that regardless of treatment methods, the risk of dying from early prostate cancer in the next 10 years is low and nearly identical. Prostate cancer is one of the most common cancers in men, and there are a number of management options for localized disease, such as active surveillance, radical prostatectomy, chemotherapy, intensitymodulated radiotherapy, radiofrequency ablation, cryotherapy, stereotactic ablative radiotherapy, particle therapy, brachytherapy, and an emerging range of focal therapies.
Prostate cancer treatment study changing the way doctors. Epidemiology of prostate cancer and benign prostatic. The incidence of this disease is highest among caucasian and africanamerican males, with reported incidences of. Articles from prostate cancer are provided here courtesy of hindawi publishing corporation. Prostate cancer and prostatic diseases covers all aspects of prostatic diseases, in particular prostate cancer overcoming barriers to performing transperineal prostate biopsies editorial much of the push to perform transperineal prostate biopsy has been driven by concerns about increasing rates of sepsis associated with the transrectal. Prostate cancer is diagnosed by digital rectal exam, prostate specific antigen psa test, and prostate biopsy. To diagnose prostate cancer, you doctor may do a digital rectal. Prostate cancer is one of the most malignancies in men in the united states, second only to skin cancer, and as a cause of cancer death in men is second only to lung cancer.
There are many studies currently being conducted to help further understand how diet and prostate cancer are related. Docetaxel is an antineoplastic chemotherapy drug, classified as a plant alkaloid, a taxane and an antimicrotubule agent. Questionnaires administered by general practitioners in five general practices in the perth metropolitan and regional areas of western australia. It occurs predominantly in men 65 years of age and older.
This emedtv health channel offers a wide range of articles on the subject and also explains how to navigate the page to find the information you need. Advanced prostate cancer can also occur in men who have already been treated for prostate cancer but their cancer has come back relapsed or recurred. Prostate cancer is rare in men younger than 40, but the chance of having prostate cancer rises rapidly after age 50. Risk factors include age, family history, ethnicity, and diet. Active monitoring as effective as surgery over 10 years. Prostate cancerincidence and mortality deathrates by race, indiana, 20052014 prostate cancer is an uncontrolled growth and spread of cells in the prostate, an exocrine gland in the male reproductive system. Serinearginine protein kinase 1 srpk1, a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion nicholas bullock, jonathan potts, andrew j simpkin, anthony koupparis, steve j harper, jon oxley, sebastian oltean. The incidence rates of both diseases are currently showing a tendency to increase. In this special theme issue of the world journal of urology, we explore several aspects of prostate cancer global epidemiology in detail. Only 25% of cancers are diagnosed before the age of 65y in europe 1. Prostate cancer journal articles brca1 and brca2 gene mutations and colorectal cancer risk a large metaanalysis finds that carriers of brca1 mutation have an increased risk of colorectal cancer.
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